Epidemiologic studies and meta‑analyses have not observed an elevated chance of genital or non-genital delivery defects (such as cardiac anomalies and limb-reduction defects) adhering to exposure to progestins before conception or throughout early pregnancy.
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The most typical utilization of MPA is in the shape of DMPA as a long-acting progestogen-only injectable contraceptive to forestall pregnancy in Women of all ages. It is an incredibly effective contraceptive when employed with rather substantial doses to prevent ovulation. MPA can be employed together with an estrogen in menopausal hormone therapy in postmenopausal Ladies to treat and prevent menopausal signs or symptoms which include hot flashes, vaginal atrophy, and osteoporosis.[3] It is used in menopausal hormone therapy specifically to prevent endometrial hyperplasia and cancer that would otherwise be induced by prolonged unopposed estrogen therapy in Ladies with intact uteruses.
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